PGIMER (Postgraduate Institute of Medical Education & Research), Dept. of Pediatrics is invited applications for its Research Internship under Social scientific responsibility of DST-SERB funded 3 years project entitled “To evaluate genetics of early-onset Systemic lupus erythematosus and functional characterization of variants detected to elucidate the disease mechanism”.
PGIMER Research Internship for Life Sciences Highlights
| Particulars | Details |
| Name of the Post | Research Internship |
| No. of Posts | 01 |
| Duration | 01 Month |
| Qualifications | MSc in Life Sciences (Completed or pursuing) Preferable Immunology, Biology, Molecular, Human Genomics, or Biotechnology |
| Principal Investigator | Dr. Amit Rawat |
| Stipend | Rs. 10,000 |
Application Procedure
Interested candidates are required to submit their applications with complete bio-data and photograph along with photocopies of certificates/testimonials by 5th June 2023.
Possible Interview Questions
1.Could you describe your background and expertise in the fields of immunology, molecular biology, or biotechnology, particularly in relation to Systemic Lupus Erythematosus (SLE) research?
Answer: I have completed my MSc in Life Science, specializing in Immunology, Molecular Biology, or Biotechnology. Throughout my studies, I have developed a strong understanding of the principles and techniques relevant to these fields. Specifically, I have acquired knowledge related to the genetics of early-onset SLE and the functional characterization of variants associated with the disease.
2. Have you participated in any research projects or conducted experiments related to genetics or disease mechanisms? If yes, could you provide some details?
Answer: Absolutely, during my academic journey, I have actively engaged in various research projects focusing on the study of genetics and disease mechanisms. For instance, I have conducted experiments analyzing gene variants associated with specific diseases and performed functional characterization of these variants. These experiences have not only provided me with valuable insights into the research process but have also equipped me with the necessary skills for this particular project.
3.What is the importance of studying early-onset systemic lupus erythematosus (SLE) and its genetic basis?
Answer: Researching early-onset SLE is of utmost significance as it allows us to comprehend the underlying genetic factors that contribute to the development and progression of the disease. By investigating the genetics of early-onset SLE, we can identify specific gene variants associated with the condition and gain insights into the molecular mechanisms involved. This knowledge has the potential to enhance diagnostic methods, facilitate personalized treatment approaches, and deepen our understanding of the disease’s pathogenesis.
4. How familiar are you with the techniques employed for the functional characterization of genetic variants?
Answer: I possess comprehensive knowledge of the techniques commonly utilized for the functional characterization of genetic variants. These techniques may encompass molecular cloning, gene expression analysis, protein-protein interactions, cell culture assays, and other relevant methodologies. During my academic training, I have gained hands-on experience with some of these techniques. Additionally, I am highly motivated to expand my knowledge and skills in this area.
5. Could you discuss your understanding of the overall objectives and scope of the project “to evaluate genetics of early-onset systemic lupus erythematosus and functional characterization of variants detected to elucidate the disease mechanism”?
Answer: The primary objective of this project is to investigate the genetic factors contributing to early-onset SLE and gain a comprehensive understanding of the disease mechanism. This entails identifying and analyzing genetic variants associated with the disease and performing functional characterization to ascertain their impact on disease progression. The project aims to elucidate the underlying molecular pathways and mechanisms involved in early-onset SLE. The knowledge derived from this research can potentially contribute to the development of more effective diagnostic and therapeutic approaches tailored to the disease.
Note: The answers given above are provided as reference examples. It is essential to customize your responses based on your unique background, expertise and knowledge.
Location
Chandigarh
